Impact of Postpartum Diagnosis on Survival of Women with Inflammatory Breast Cancer.

ABSTRACT:

Background

Postpartum diagnosis of breast cancer confers increased risk of metastasis and death, possibly because of protumorigenic pathways that occur after weaning. We sought to evaluate the impact of postpartum diagnosis on survival in patients with inflammatory breast cancer (IBC).

Methods

We performed a retrospective analysis of patients with nonmetastatic IBC enrolled in a prospective registry (2007-2023). Kruskal-Wallis, χ2, and Fisher exact tests were used to compare between postpartum groups. The Kaplan-Meier method and log-rank tests were used for survival estimates.

Results

Among 320 patients with IBC, 25 (7.8%) were nulliparous, 31 (9.7%) were 0 to 5 years postpartum, 26 (8.1%) were 6 to 10 years postpartum, 56 (17.5%) were 11 to 20 years postpartum, and 1

SUBMITTER: Chen JH 

PROVIDER: S-EPMC12536895 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature