The effectiveness of digital cognitive intervention in patients with traumatic brain injury: systematic review and meta-analysis.

ABSTRACT:

Objective

This meta-analysis aims to quantitatively evaluate the effects of digital cognitive intervention (non-immersive computer- and immersive virtual reality (VR)-based) on cognitive function and psychosocial outcomes in patients with traumatic brain injury (TBI), and to explore potential moderating factors.

Methods

A systematic search was conducted in PubMed, the Cochrane Library, Embase, and Web of Science databases from their inception to April 3, 2025. Standardized mean differences (SMDs) and 95% confidence intervals (CIs) were calculated to estimate effect sizes, and heterogeneity was assessed using the I² statistic.

Results

A total of 16 studies were included; 9 employed computer-based cognitive interventions and 7 used VR-based interventions. The

SUBMITTER: Chi K 

PROVIDER: S-EPMC12537419 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature