Major adverse kidney events among chronic kidney disease patients with vitamin D deficiency.

ABSTRACT:

Objective

This study aimed to evaluate the association of vitamin D deficiency (VDD) and major adverse kidney events (MAKEs) among patients with chronic kidney disease (CKD).

Methods

We conducted a retrospective cohort study using the TriNetX Global Collaborative Network. Eligible participants were adults with CKD who had a vitamin D testing between January 01, 2010 and January 31, 2025. According to the status of vitamin level, individuals were classified into two groups, VDD group and control group. Propensity score matching (PSM) was applied to balance baseline characteristics between groups. The primary outcome was the risk of MAKEs during one-year follow-up, while secondary outcomes included all-cause mortality and all-cause hospitalization.

Results

After PSM, 29

SUBMITTER: Lin YM 

PROVIDER: S-EPMC12537428 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature