Log odds of negative lymph nodes/T stage as a novel predictor of post-resection outcome in non-small cell lung cancer patients.

ABSTRACT:

Background

Surgery with systematic lymph node (LN) dissection remains the primary treatment for early-stage and locally advanced operable non-small-cell lung cancer (NSCLC). However, the effect of the log odds of negative lymph nodes/T stage (LONT) in NSCLC remains unclear. This study aims to evaluate the correlation between LONT and prognosis of stage I-III NSCLC patients who underwent resection.

Methods

Clinical data from patients who underwent NSCLC resection were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. The log odds of negative LONT, defined as log(NLNs + 1)/T stage, was calculated for each patient. The nonlinear relationship between LONT and overall survival (OS) and lung cancer-specific survival (LCSS) was evaluated using the cubi

SUBMITTER: Shao L 

PROVIDER: S-EPMC12537637 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature