Risk factors for thoracic aortic aneurysm and dissection among diabetic patients: a nationwide population-based study.

ABSTRACT:

Background

Diabetes mellitus (DM) has been reported to be associated with decreased risk for thoracic aortic aneurysm and dissection (TAAD). However, risk factors for TAAD in diabetic patients remain undetermined. This study aims to investigate diabetes-specific risk factors for TAAD development in diabetic patients.

Methods

This population-based study utilized the National Health Insurance Service database in Republic of Korea. We followed 2,328,347 type 2 DM patients undergoing health check-ups from 2009 to 2012 until new TAAD diagnosis, death, or December 31, 2019. Cox proportional-hazards regression models were used to identify risk factors for TAAD development.

Results

TAAD was newly diagnosed in 0.02% (4,512/2,328,347) of patients. In the fully-adjusted model in

SUBMITTER: Lim SK 

PROVIDER: S-EPMC12537662 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature