Sensorimotor perturbation-induced cortical responses by a novel PES system: analysis of the N1 component in healthy adults and Parkinson's disease.

ABSTRACT: Perturbation-evoked potentials (PEPs) have been widely used to investigate static and dynamic perturbations on postural and motor control through analysis of cortical responses. In this pilot study, we present an innovative approach using IoT-based Perturbatory Electrical Stimulation (PES) during treadmill walking to assess cortical responses in healthy adults (N = 6) and individuals with Parkinson's disease (N = 4), with a focus on the N1 component. This approach integrates PES and EEG systems through an Internet of Things (IoT) framework utilizing the MQTT protocol, enabling synchronized and wireless data acquisition during gait. The results indicated significant differences in N1 latency (p = 0.005), with the Parkinson's disease group presenting higher latencies in

SUBMITTER: Rathke CL 

PROVIDER: S-EPMC12537702 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature