Efficacy of botanical extracts for knee osteoarthritis: a network meta-analysis of randomized controlled trials.

ABSTRACT:

Background

Traditional botanical drugs and medicinal plants, along with their metabolite extracts, have exhibited considerable potential in the management of knee osteoarthritis (KOA) due to their natural properties, favorable safety profiles, and minimal adverse effects.

Objective

This study aimed to evaluate the therapeutic efficacy of various botanical and medicinal plant extracts on KOA. Search Methods: We conducted a comprehensive literature search across PubMed, Embase, Cochrane Library, and Web of Science, focusing exclusively on randomized controlled trials (RCTs) that investigated the efficacy of botanical and medicinal plant extracts for KOA. Selection Criteria: Studies were included if they met the following criteria: (1) experimental groups receiving single botan

SUBMITTER: Yan C 

PROVIDER: S-EPMC12537895 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature