Association of standard dietary inflammatory index with diabetic retinopathy in diabetes: A prospective cohort study.

ABSTRACT:

Background and aims

Diabetic retinopathy (DR) is a major cause of vision impairment, and its development is linked to chronic inflammation. Investigating the role of dietary patterns, specifically the standard dietary inflammatory index (DII), may provide insights into modifiable risk factors for DR.

Objective

To quantify the impact of dietary inflammatory potential (assessed via the standard DII) on both risk of DR and structural alterations across individual retinal layers.

Methods

We conducted a prospective cohort study using data from the UK Biobank. Cox proportional hazards models and restricted cubic splines were used to examine the correlation between the standard DII and DR in three adjusted models. Sensitivity analyses were performed to test the robustness of

SUBMITTER: Xu Z 

PROVIDER: S-EPMC12538057 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature