Association between sedentary behavior, physical activity, and the triglyceride glucose index and its derived indices: evidence from NHANES 2013-2018.

ABSTRACT:

Background

While sedentary behavior and physical activity have been associated with the TyG index, their associations with TyG-derived indices and their potential interaction remain unclear.

Objective

This study aimed to examine the independent and interactive associations of sedentary behavior and physical activity with the TyG index and its derived indices.

Methods

This cross-sectional analysis used NHANES 2013-2018 data. We employed survey-weighted multivariate regression and restricted cubic splines to evaluate independent and nonlinear associations. Multiplicative interaction terms were used to examine if physical activity levels altered the association between sedentary behavior and outcomes.

Results

After multivariable adjustment, longer sedentary time w

SUBMITTER: Du M 

PROVIDER: S-EPMC12538063 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature