The association between preoperative anxiety and chronic post-surgical pain after general anaesthesia, a systematic review and meta-analysis.

ABSTRACT:

Background

Chronic post-surgical pain (CPSP) is a burden for both patients and healthcare, yet current treatment options are insufficient. Previous studies indicate preoperative anxiety as a risk factor for developing CPSP, yet no high-quality review exists. This study aims to systematically review the relationship between increased preoperative anxiety and the incidence of new CPSP.

Methods

Four databases were used to identify relevant studies for a systematic review and meta-analysis. Inclusion criteria included adult patients undergoing surgical procedures under general anaesthesia, measuring preoperative anxiety with validated tools, and postoperative pain at least 3 months after surgery. Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guideli

SUBMITTER: Bakker-Bons M 

PROVIDER: S-EPMC12538085 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature