Integrated Piezoelectric Vibration and In Situ Force Sensing for Low-Trauma Tissue Penetration.

ABSTRACT: Precision-controlled microscale manipulation tasks-including neural probe implantation, ophthalmic surgery, and cell membrane puncture-often involve minimally invasive membrane penetration techniques with real-time force feedback to minimize tissue trauma. This imposes rigorous design requirements on the corresponding miniaturized instruments with robotic assistance. This paper proposes an integrated piezoelectric module (IPEM) that combines high-frequency vibration-assisted penetration with real-time in situ force sensing. The IPEM features a compact piezoelectric actuator integrated with a central tungsten probe, generating axial micro-vibration (4,652 Hz) to enable smooth tissue penetration while simultaneously measuring contact and penetration forces via the piezoelectric effect. Exten

SUBMITTER: He B 

PROVIDER: S-EPMC12538090 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature