Probiotic pasta consumption improves lipid metabolism and reduces gut permeability in overweight and obese adults: a randomized controlled trial.

ABSTRACT: This study investigates the effects of a Shouchella clausii UBBC-07 spore-enriched pasta (ProbP) compared to a conventional pasta (ConP) on metabolic health and gut microbiome composition in overweight and obese individuals. A 4-weeks randomized controlled trial was conducted with 40 participants (17 females and 23 males, aged 35.4 ± 2.0 years, body mass index 27.6 ± 0.4 kg/m²), all habitual pasta consumers. Participants were randomly assigned to replace their habitual pasta with 80 g/day of either ProbP (n = 20) or ConP (n = 20) while maintaining their regular diet. Blood, urine, and fecal samples were collected at baseline and after 4 weeks to assess changes in clinical variables and gut microbiome composition. Consumption of ProbP led to an 11 % increase in serum high-

SUBMITTER: Tagliamonte S 

PROVIDER: S-EPMC12538098 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature