Circulating microRNAs and endometriosis: a comprehensive analysis and validation of identified biomarkers in an Indian population.

ABSTRACT:

Graphical abstract

Abstract

Endometriosis is a prevalent condition where tissue similar to the uterine lining grows outside the uterus, causing pain and infertility. Diagnosing endometriosis typically requires invasive procedures such as laparoscopy. MicroRNAs (miRNAs) have emerged as promising noninvasive biomarkers for various diseases, including endometriosis. However, studies have shown inconsistent miRNA expression patterns across populations. This study aims to validate circulating miRNAs as biomarkers for endometriosis in Indian women, addressing the limited validation data available for this population. This comprehensive review identified nine circulating miRNAs based on reproducibility and consistent expression patterns. Women with advanced-stage endometriosis (n

SUBMITTER: Chauhan S 

PROVIDER: S-EPMC12538115 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature