Hyperdilute Radiesse Preserves Facial Volume in Glucagon-Like Peptide-1 Receptor Agonist Users Undergoing Rapid Weight Loss.

ABSTRACT: Biostimulators like hyperdiluted calcium hydroxylapatite-carboxymethylcellulose (CaHA-CMC; Radiesse, Merz North America, Franksville, WI) are effective in promoting neocollagenesis and restoring facial volume. The emergence of glucagon-like peptide-1 (GLP-1) receptor agonists (GLP1RAs) for weight loss has introduced a subset of patients experiencing rapid weight loss with associated facial-volume changes, colloquially known as "Ozempic Face" (Novo Nordisk, Bagsvaerd, Denmark). This case series describes 4 patients on GLP1RAs who, despite rapid weight loss, maintained facial volume following treatment with hypderilute CaHA-CMC in the lower face. Four patients undergoing rapid weight loss with GLP1RA were retrospectively evaluated following hyperdilute (1:3) CaHA-CMC treatment in the lower f

SUBMITTER: Durairaj KK 

PROVIDER: S-EPMC12538281 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature