Snapshot Genomic Surveillance Reveals Insights into Antimicrobial Resistance and Lineage Diversity of Uropathogens in Older Adults in Queensland.

ABSTRACT:

Background

Community-acquired urinary tract infections (UTIs) are a significant health concern in older adults. However, few studies have investigated the epidemiology of uropathogens across diverse settings where older adults reside.

Methods

In this study, we whole-genome sequenced urinary isolates of Escherichia coli, Klebsiella species, and Enterobacter cloacae complex collected from individuals aged 70 and over living in the community and residential aged care facilities (RACFs) in Queensland, Australia. We investigated the prevalence of antimicrobial resistance (AMR), pathogen population structure, and transmission dynamics across the settings.

Results

E. coli was most frequently identified (82.2%, 447/544), followed by K. pneumonia

SUBMITTER: Permana B 

PROVIDER: S-EPMC12538390 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature