Novel B,N-doped carbon quantum dot fluorescence quenching method for sensitive and green determination of lisinopril: mechanistic insights from quantum calculations and sustainable analytical approach.

ABSTRACT: A novel, sensitive, and environmentally friendly fluorescence quenching method was developed for lisinopril determination using boron and nitrogen co-doped carbon quantum dots (B,N CQDs) as fluorescent probes. The B,N CQDs exhibited uniform nanoparticles with mean diameter of 3.97 nm and intense blue fluorescence with maximum excitation at 360 nm and emission at 429 nm. Upon increasing lisinopril concentration, a quenching of the B,N CQDs fluorescence was observed in a concentration-dependent manner. The fluorescence quenching mechanism was investigated through Stern-Volmer analysis, thermodynamic studies, and quantum mechanical calculations. Static quenching via ground-state complex formation was confirmed with Stern-Volmer constants (K _sv) decreasing from 7.94 ×

SUBMITTER: Alqahtani T 

PROVIDER: S-EPMC12538397 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature