Massive multinodular goiter causing airway compression: A case series.

ABSTRACT:

Introduction

Severe multinodular goiter (MNG) with extreme thyromegaly is a life-threatening condition due to airway and vascular compression. While rare, it demands a specialized, multidisciplinary approach to prevent catastrophic perioperative complications. This case series outlines a structured management protocol for this high-risk population.

Case presentation

We present three consecutive, eligible patients with severe MNG managed per a predefined protocol. All exhibited Pemberton's sign and > 70 % tracheal narrowing on imaging, with thyroid weights ranging from 800 g to 1.3 kg. Primary symptoms were progressive dyspnea, stridor, and thoracic inlet obstruction.

Discussion

A standardized protocol was employed, encompassing preoperative optimization (e.g., correct

SUBMITTER: Farahani PK 

PROVIDER: S-EPMC12538451 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature