Biocompatible Multifunctional Polymeric Material for Mineralized Tissue Adhesion.

ABSTRACT: This study develops a biocompatible multifunctional thiol-ene resin system for adhesion to dentin mineralized tissue. Adhesive resins maintain the strength and longevity of dental composite restorations through chemophysical bonding to exposed dentin surfaces after cavity preparations. Monomers of conventional adhesive systems may result in inhomogeneous polymer networks and the release of residual monomers that cause cytotoxicity. In this study, a one-step multifunctional polymeric resin system by incorporating trimethylolpropane triacrylate (TMPTA) and bis[2-(methacryloyloxy)ethyl] phosphate (BMEP) is developed to enhance both mechanical properties and adhesion to dentin. Molecular dynamics simulations identify an optimal triacylate:trithiol ratio of 2.5:1, which is consistent with rheol

SUBMITTER: Luo Y 

PROVIDER: S-EPMC12538523 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature