Epoxide Alcoholysis over M‑BEA Zeolites: Effects of Alcohol Chain Length on Rates and Regioselectivities.

ABSTRACT: The structures of nucleophilic reactants affect their coordination behavior among solvent molecules and kinetics of reactions with surface intermediates within the confines of fluid-filled pores of zeolites and other microporous materials. Consequently, rates and regioselectivities of diverse chemistries may depend sensitively on nucleophile identity in manners not observed for classic fluid phase reactions. Here, we examine the impact of varying the primary alcohol (ROH) chain length on the kinetics of 1,2-epoxybutane (C₄H₈O) ring-opening within Brønsted (Al-BEA) and Lewis acid (Zr-BEA) zeolites. Turnover rates increase by factors of ∼6 (Al-BEA) and 4-fold (Zr-BEA) between methanol and 1-hexanol, yet the reaction mechanisms remain comparable. Despite modest rate diff

SUBMITTER: Locht H 

PROVIDER: S-EPMC12538543 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature