Dual-emission nitrogen-doped carbon dots for ratiometric and smartphone-based detection of levofloxacin.

ABSTRACT: Levofloxacin (LEV) is a third-generation fluoroquinolone commonly applied in treatment against infections in both humans and animals. However, its overuse has led to increasing concerns regarding environmental contamination, health risks, and the emergence of antibiotic-resistant bacteria. In this study, we present a novel dual-emission ratiometric fluorescence probe for the detection of LEV, utilizing the intrinsic green fluorescence of LEV as the sensing signal and blue-emissive nitrogen-doped carbon dots (N-CDs) as an internal reference. N-CDs were synthesized via a one-pot hydrothermal method using 4-aminoantipyrine (4AA) and hydrazine hydrate (HH) as precursors. Elemental analysis revealed a high nitrogen content (22.1%), which enhanced the photoluminescence properties, achievi

SUBMITTER: Abubakr SA 

PROVIDER: S-EPMC12538674 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature