Network meta-analysis of high tibial osteotomy combined with different bone defect filler materials for medial compartment knee osteoarthritis.

ABSTRACT:

Objective

This study aims to systematically review and analyze the clinical and radiographic outcomes of high tibial osteotomy (HTO) combined with various bone defect filler materials for the treatment of medial compartment knee osteoarthritis (MCKOA). In light of the increasing adoption of enhanced recovery after surgery (ERAS) principles, we further seek to refine treatment strategies for MCKOA by comparing the therapeutic effects of different filler materials.

Methods

We performed a comprehensive literature search of studies published from database inception to July 1, 2024, across PubMed, Medline, Embase, the Cochrane Library, Web of Science, and Scopus. Using a network meta-analysis framework, we systematically assessed clinical comparative studies involving two or more

SUBMITTER: Pei Z 

PROVIDER: S-EPMC12538742 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature