Association of lung field area with mortality in Mycobacterium avium complex lung disease: a longitudinal cohort study.

ABSTRACT:

Background

Nontuberculous mycobacteria (NTM), particularly the Mycobacterium avium complex (MAC), is becoming a global health burden with increasing incidence worldwide. Previous studies have linked pulmonary function impairment with increased mortality in NTM lung disease, suggesting that lung volume may be a critical predictor of mortality. The objective of this study was to assess the prognostic value of lung field area (LFA) in predicting all-cause mortality among patients with MAC lung disease.

Methods

We conducted a longitudinal cohort study of 232 patients diagnosed with MAC lung disease at NHO Fukuoka National Hospital from April 1996 to December 2021. Quantitative CT image analysis was performed to measure LFA. Statistical analysis included Kaplan-Meier curves and C

SUBMITTER: Ogata H 

PROVIDER: S-EPMC12538755 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature