Physical activity and cardiovascular-metabolic disease risk across cardiovascular-kidney-metabolic syndrome stages: a population-based cohort study.

ABSTRACT:

Background

Cardiovascular-kidney-metabolic (CKM) syndrome has become a major global health burden, while physical activity, as an important lifestyle intervention, remains unclear regarding its protective effects on disease risk across different CKM stages.

Methods

We utilized data from the China Health and Retirement Longitudinal Study (CHARLS), including 7,159 participants. According to the quartile distribution of total weekly metabolic equivalents, all participants were divided into four groups: Q1 group (≤ 1732.5 MET-min/week, reference group), Q2 group (1732.6-4158.0 MET-min/week), Q3 group (4158.1-9744.0 MET-min/week), and Q4 group (> 9744.0 MET-min/week). For CKM analysis, participants were categorized into two groups: low-risk CKM (stages 0-2) and high-risk CKM (sta

SUBMITTER: Zhao W 

PROVIDER: S-EPMC12538840 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature