Pre-exposure prophylaxis use and discontinuation among Brazilian gay, bisexual, and other men who have sex with men: examining the role of internalized homonegativity and discrimination.

ABSTRACT:

Background

Pre-exposure prophylaxis (PrEP) is a highly effective HIV prevention strategy yet use and persistence among populations at high vulnerability to HIV in Brazil remains suboptimal. We sought to quantify internalized homonegativity and discrimination using multi-item validated instruments and to estimate their associations with PrEP use and discontinuation among gay, bisexual, and other men who have sex with men (MSM).

Methods

A cross-sectional, web-based survey was conducted from November 2021 to January 2022, recruiting a convenience sample of MSM through dating apps and social media. The survey assessed sociodemographic characteristics, sexual behavior, substance use, HIV transmission knowledge (using the HIV Knowledge Assessment tool), internalized homonegativity

SUBMITTER: Barreto KM 

PROVIDER: S-EPMC12538878 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature