Advanced stage melanoma during pregnancy: recommendations from a retrospective, multicentre, registry-based study.

ABSTRACT:

Background

Diagnosis and treatment of advanced melanoma during pregnancy represents a major challenge, with scarce data on outcome or management available. Therefore, the Melanoma Pregnancy Taskforce collected real-world data to understand the current management approaches.

Methods

This retrospective, multicenter database included patients who were either diagnosed with advanced melanoma (newly diagnosed or recurrent) during pregnancy (group 1) or conceived while on systemic treatment (group 2) between 01/01/2011 and 07/31/2024. Information regarding patient, primary tumor and advanced melanoma characteristics, intervention or treatment during pregnancy, and outcomes of mother and fetus were collected using a standardized, de-identified form.

Findings

72 women from se

SUBMITTER: Borgers JSW 

PROVIDER: S-EPMC12538904 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature