Development of an efficient approach to boost fused deposition modeling (FDM) printing of felodipine-HPMC tablets for enhanced physical stability.

ABSTRACT: Fused deposition modeling (FDM) is a widely investigated 3D printing technology for pharmaceutical applications because of its advantages, including easy access of equipment and cost-effectiveness. Despite its versatility, the FDM 3D printing process is multi-step, time-consuming and resource intensive, and requires a holistic selection of material and formulation design to achieve successful printing. The aim of this work is to develop an efficient approach to streamline FDM 3D tablet-printing processes, as well as to explore the factors that may influence the physical stability of the tablets produced. For this purpose, the polymer Affinisol™ HPMC HME 15LV and the model drug felodipine were selected for printing process evaluation, and the produced drug-polymer tablets were investigated

SUBMITTER: Ren H 

PROVIDER: S-EPMC12538912 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature