A retrospective and comprehensive analysis of excess life-years lost, mortality risk, and cause of death among severe mental illness in China.

ABSTRACT:

Background

Individuals with severe mental illness (SMI) experience higher mortality rates than the general population. We conducted a comprehensive, population-based study to quantify the excess life-years lost (LYLs), mortality risks, and cause of death among SMIs.

Methods

Using data from the Jiangsu Province Management Information System for Patients with SMI, we identified 321,436 SMI patients in Jiangsu, China, between January 2014 and December 2022; 33,947 of them died during follow-up. We calculated the excess LYLs for each type of SMI and estimated the standardized mortality ratios (SMRs) for all-cause and specific-cause mortality among individuals with four types of SMIs.

Results

The excess LYLs in four types of SMIs were as follows: for schizophrenia, 12.87 y

SUBMITTER: Fang X 

PROVIDER: S-EPMC12538965 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature