Primary adenosquamous carcinoma of the prostate with rapid elevation of prostate-specific antigen: a case report.

ABSTRACT:

Background

Primary adenosquamous carcinoma of the prostate is an extremely rare and aggressive variant, accounting for less than 1% of all prostate cancers. Due to its rarity, the prognosis is poor, with no established treatment. Prostate-specific antigen levels are typically within the normal range in primary adenosquamous carcinoma of the prostate.

Case presentation

We present the case of a 57-year-old East Asian male in whom pathological and imaging findings led to the diagnosis of primary adenosquamous carcinoma of the prostate. His prostate-specific antigen levels were initially high and continued to increase rapidly thereafter to 161.89 ng/ml. Although hormonal therapy achieved a reduction in prostate-specific antigen levels, the disease progressed rapidly, with extens

SUBMITTER: Shigehisa R 

PROVIDER: S-EPMC12539044 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature