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ABSTRACT: Objectives
This study aimed to investigate the synergistic effects of co-exposure to occupational heat and noise on multi-system health outcomes among Chinese workers, and to examine the mediating role of systemic inflammation, indicated by white blood cell (WBC) count.Methods
A cross-sectional analysis was conducted using data from the Fujian Workplace Occupational Hazards Comprehensive Surveillance Program (2020-2022), encompassing 10,275 workers from the manufacturing, petrochemical, mining, and construction industries. Multivariate logistic regression, relative excess risk due to interaction (RERI), random forest with SHAP values, and mediation analysis were used to explore interaction effects and mediating pathways.Results
Co-exposure to heat and noise in the w
SUBMITTER: Li M
PROVIDER: S-EPMC12539164 | biostudies-literature | 2025 Oct
REPOSITORIES: biostudies-literature