Elective single morula transfer achieved better clinical outcomes than two cleavage embryos transfer in fresh IVF-ET cycles.

ABSTRACT:

Background

Assisted reproductive technology (ART) effectively treats infertility yet often results in multiple pregnancies. Optimizing clinical pregnancy rates while minimizing multiples remains challenging. Key considerations for ART providers include embryo transfer timing, number, and developmental stage. While double cleavage-stage and single blastocyst transfers are common, limited data exists on the intermediate strategy of single morula transfer.

Objective

This research aimed to assess whether elective single morula transfer (eSMT) on Day 4 yields clinical outcomes comparable to double cleavage-stage embryo transfer (DCT) on Day 3.

Methods

A retrospective propensity-matched cohort study compared DCT and eSMT in IVF, with 156 matched cases per group. Primary out

SUBMITTER: Feng Q 

PROVIDER: S-EPMC12539196 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature