Spain's Sarcoidosis Mortality: An Evolving Public Health Challenge.

ABSTRACT:

Objective

To comprehensively analyze national trends in sarcoidosis mortality in Spain between 1999 and 2023, with a focus on demographic differences and changes over time.

Material and methods

This nationwide ecological study analyzed death registry data for sarcoidosis (ICD-10 code D86) from the Spanish National Institute of Statistics. Age-standardized mortality rates (ASMRs) were calculated by sex and age. Joinpoint regression assessed temporal trends and annual percentage changes (APCs).

Results

Spain recorded 1053 sarcoidosis deaths between 1999 and 2023, with women accounting for 61.8%. Overall deaths rose, peaking at 72 in 2022. Mortality was heavily concentrated among those aged ≥ 65 years (75.8% of deaths). Age-specific mortality rates were negligible under

SUBMITTER: Cayuela L 

PROVIDER: S-EPMC12539305 | biostudies-literature | 2025 Oct-Dec

REPOSITORIES: biostudies-literature