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ABSTRACT: Background
Transcatheter paravalvular leak (PVL) closure is typically guided by fluoroscopy; however, fluoroscopic imaging may not always be available and can be unsuitable for select patient populations.First-in-human/early reports summary
We present the first-in-human case of successful PVL closure performed entirely under the guidance of three-dimensional transesophageal echocardiography (3D-TEE).Discussion
The case demonstrates that 3D-TEE alone can effectively guide catheter navigation and device deployment, with optimal clinical outcomes.Novelty
To the best of our knowledge, this is the first reported experience of percutaneous PVL closure without fluoroscopy.Take-home message
Fluoroscopy-free PVL closure is feasible under real-time 3D-TEE guid
SUBMITTER: Pang K
PROVIDER: S-EPMC12539460 | biostudies-literature | 2025 Sep
REPOSITORIES: biostudies-literature