Helicobacter pylori Infection Is a Risk Factor for Severe Hyperemesis Gravidarum Requiring Prolonged Hospitalization.

ABSTRACT:

Objective

This retrospective study investigated the relationship between Helicobacter pylori (H. pylori) infection and prolonged hospitalization in patients with severe hyperemesis gravidarum (HG). We also aimed to identify other factors associated with extended hospital stays.

Methods

We analyzed data from 164 patients with severe HG. The patients were initially divided into two groups based on their anti-H. pylori IgG antibody status (positive vs. negative). Subsequently, a second analysis stratified all patients into a short-stay group (< 21 days) and a long-stay group (≥ 21 days).

Results

Patients who were positive for anti-H. pylori IgG antibodies had significantly longer hospital stays (median 24 vs. 15 days, p = 0.032). In a univariate analysis, anti-H. pylori

SUBMITTER: Kurashina R 

PROVIDER: S-EPMC12540016 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature