Immune and inflammatory mechanisms in asthma: insights into epigenetic modifications.

ABSTRACT:

Background

Asthma is a chronic respiratory disease influenced by genetic and environmental factors. Emerging evidence highlights epigenetics as a key regulatory mechanism in asthma development.

Objective

This research aimed to summarize current evidence on immune-epigenetic mechanisms in asthma and to identify global research hotspots through bibliometric analysis.

Methods

A systematic search was conducted in the Web of Science Core Collection(WoSCC) and Scopus databases for studies published between 1980 and July 2025. Following PRISMA guidelines, duplicate removal and quality control were performed. Eligible articles were analyzed using CiteSpace, VOSviewer, and the R bibliometrix package to evaluate publication trends, countries, institutions, authors, journals, co

SUBMITTER: Fan H 

PROVIDER: S-EPMC12540441 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature