Infective Endocarditis 19 Months After Transcatheter Ostium Secundum Atrial Septal Defect Closure in a 6-Year-Old.

ABSTRACT:

Background

Infective endocarditis (IE) after transcatheter atrial septal defect (ASD) closure is rare.

Case summary

We report the case of a 6-year-old girl who developed methicillin-resistant Staphylococcus aureus IE 19 months after ASD closure with an Amplatzer device. She presented with severe sepsis, a large vegetation on the right atrial side of the occluder, and moderate tricuspid regurgitation. Despite empirical antibiotic therapy, persistent bacteremia mandated surgical removal of the device, ASD closure with a pericardial patch, and tricuspid valve repair. Six weeks of targeted antibiotics led to a favorable 1-year outcome.

Discussion

This case, alongside other reports of late-onset IE after transcatheter ASD closure, highlights that although rare, such infect

SUBMITTER: Gery C 

PROVIDER: S-EPMC12540456 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature