Impact of GFR on Mortality Risk After Biliopancreatic Diversion: Challenges and Pitfalls for the Clinician.

ABSTRACT:

Background

Assessing kidney function in bariatric patients remains challenging, as both obesity and malnutrition act as confounding factors. Although short-term cardiovascular and renal benefits of biliopancreatic diversion (BPD) have been documented, the long-term effects of estimated glomerular filtration rate (eGFR) improvement remain unclear.

Methods

To compare different eGFR formulas based on creatinine and to evaluate the relationship between short- and long-term eGFR changes and mortality risk in patients undergoing BPD.

Results

284 patients were enrolled. Mean pre-surgery BMI, creatinine, and eGFR were 47.0 ± 9.3, 0.87 ± 0.21 mg/dl, and 75.3 ± 15.9 mL/min/1.73m², respectively. During a mean follow-up of 16 ± 9 years, 40 patients (16%) died. BMI decr

SUBMITTER: Russo E 

PROVIDER: S-EPMC12540522 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature