MiRNA‒microbiome correlations in Bos indicus feed efficiency.

ABSTRACT: The fecal microbiome is emerging as an essential component of the gut microbiota and host metabolism, whereas in cattle, fecal microbiome characterization is still needed. Recent evidence indicates that small RNAs, such as miRNAs, may be isolated from feces and involved in host-microbe interactions. In this study, fecal samples were collected from the rectal ampulla of Nelore bulls that were phenotypically divergent in terms of residual feed intake (RFI). miRNA sequencing and 16S rRNA gene (V3-V4 region) sequencing were performed to reveal the associations between host miRNAs and microbiome composition and their relationships with the feed efficiency phenotype. Among the 162 identified fecal miRNAs, seven were more expressed in the inefficient group: bta-miR-27b, bta-miR-30a, bta-miR-126,

SUBMITTER: de Oliveira PSN 

PROVIDER: S-EPMC12540843 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature