Effect of the intravenous acetaminophen clinical pathway on postoperative analgesia in spinal fusion surgery.

ABSTRACT: Post spinal-fusion surgery pain levels are high, posing challenges for pain management. We introduced around-the-clock (ATC) administration of intravenous acetaminophen in the clinical pathway for spinal-fusion surgery. This single-center, retrospective observational study investigated effects of its introduction on postoperative pain levels and recovery adjusting for background variables. Adult patients who underwent elective spinal-fusion surgery were categorized into pre- and post-groups based on the timing of ATC acetaminophen introduction. The primary endpoint was the numerical rating scale (NRS) score at rest in the morning of the first postoperative day (POD). Secondary endpoints were NRS scores on POD1-3, rescue analgesic use, postoperative nausea and vomiting within 48 h, food int

SUBMITTER: Taniguchi H 

PROVIDER: S-EPMC12540975 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature