Relationship between dementia diagnostic characteristics and severity of depressive symptoms in a cross-sectional analysis of HOMESIDE baseline data.

ABSTRACT: Depression is a common comorbidity in dementia, with prevalence ranging from 20 to 60% across different countries. This study examined whether depressive symptom severity levels differ by dementia characteristics and country of residence in people living with dementia. This cross-sectional analysis used baseline data from 376 participants in the HOMESIDE trial. Linear regression models examined differences in depressive symptom severity levels by dementia stage, type, severity, and country. In this sample (57% male, mean age 76.6 years), depressive symptom scores were higher for people with severe cognitive impairment than those with mild dementia (MMSE 24-30) (adjusted mean difference: 3.78, 95% CI 1.60-5.96). Mean depressive symptom severity was lower in Norway, Germany, and United Kingd

SUBMITTER: Bukowska AA 

PROVIDER: S-EPMC12541064 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature