Efficacy of Herbal Medicine Therapy Combined With Palliative Chemotherapy in Unresectable Advanced NSCLC: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Lung cancer, a leading cause of mortality, is often complicated by severe treatment-related side effects. Traditional herbal medicine (THM), particularly Fuzheng-Based Qi and Yin Therapy (FBQYT), has emerged as a promising adjuvant therapy to mitigate these effects and enhance immune response. This meta-analysis evaluates the efficacy and safety of THM as an adjunct to palliative chemotherapy.

Methods

A systematic search was conducted in PubMed, EMBASE, ScienceON, RISS, KMBASE, OASIS, Cochrane Library, KISS, CNKI, and CiNii up to April 2025. Outcomes included tumor response, quality of life (QoL), adverse drug reactions (ADRs), and tumor markers. Eighty randomized controlled trials (RCTs) involving stage III/IV lung cancer patients were analyzed using Review Manag

SUBMITTER: Lee KJ 

PROVIDER: S-EPMC12541183 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature