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Advanced Echocardiographic Assessment Predicts 1-Year Mortality in Critically Ill Patients With Pulmonary Arterial Hypertension.


ABSTRACT:

Background

Despite advancements in diagnosing and managing pulmonary arterial hypertension (PAH), critically ill patients with PAH experience high mortality and current risk scores offer limited utility for risk stratification.

Objectives

The purpose of this study was to evaluate whether echo-derived right heart metrics improve risk prediction for in-hospital and 1-year mortality in critically ill PAH patients.

Methods

We analyzed PAH patients admitted to the intensive care unit from January 2010 to December 2020, with follow-up through January 2025. Echocardiographic assessments included right atrium (RA) area and phasic function, tricuspid annular plane systolic excursion (TAPSE), fractional area change, regional and global right ventricular (RV) free wall strain (R

SUBMITTER: Mombeini H 

PROVIDER: S-EPMC12541211 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature