Newly Diagnosed Atrial Fibrillation Indicators in Cryptogenic Stroke Survivors' P-Wave Indices: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Atrial fibrillation (AF) is the most common arrhythmia and a major cause of ischemic stroke recurrence. Cryptogenic stroke (CS) survivors face a higher risk for newly diagnosed AF (NDAF), with subtle ECG markers-prolonged P-wave duration (PWDur) and increased P-wave dispersion (PWDis)-potentially serving as early indicators. We aimed to quantify baseline PWDur and PWDis differences between CS survivors with NDAF and those in sinus rhythm.

Methods

Following PRISMA guidelines, we systematically searched nine databases through January 2025 for observational studies assessing baseline P-wave indices in adult CS patients in sinus rhythm. Data extraction and risk of bias assessment using the ROBINS-E tool were performed independently. Pooled mean differences (MD) with 9

SUBMITTER: Balweel H 

PROVIDER: S-EPMC12541236 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature