Long-term follow-up after initial negative prostate biopsy-comparison of conventional transrectal ultrasound biopsy and mpMRI/transrectal ultrasound fusion guided biopsy.

ABSTRACT:

Background

Men after an initial negative transrectal ultrasound (TRUS)-guided prostate biopsy have a low risk of prostate cancer (PCa) diagnosis and mortality during follow-up. It is unknown whether an initial negative multi-parametric magnetic resonance imaging (mpMRI)-guided biopsy is associated with the same risk of PCa diagnosis and mortality during follow-up. The present study aimed to describe the risk differences of developing localized, metastatic or deadly PCa after either a negative TRUS or mpMRI-guided prostate biopsy.

Methods

Men after an initial negative prostate biopsy at our institution between 2005-2021 were retrospectively identified and divided into two groups, whether they received an mpMRI prior to the biopsy [magnetic resonance imaging (MRI) group] or no

SUBMITTER: Scherer TP 

PROVIDER: S-EPMC12541502 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature