Comparative study of bronchoscopic and CT-guided percutaneous microwave ablation for inoperable non-small cell lung cancer.

ABSTRACT:

Background

Patients with inoperable stage I non-small cell lung cancer (NSCLC) have limited treatment options. Microwave ablation (MWA) offers a promising alternative. This study aims to compare the clinical efficacy and safety of computed tomography (CT)-guided percutaneous transthoracic microwave ablation (PTMA) and bronchoscopic transbronchial microwave ablation (BTMA).

Methods

A total of 126 patients with stage I NSCLC who were not candidates for surgery underwent PTMA or BTMA. Outcomes evaluated included complete ablation rate, local control rate (LCR), progression-free survival (PFS), technical success, procedure-related complications, and lesion size changes. Subgroup analyses were conducted based on age, nodule size, and nodule density.

Results

The 6-month com

SUBMITTER: Wang F 

PROVIDER: S-EPMC12541657 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature