Biopsy-proven acute eosinophilic myocarditis as the initial manifestation of severe primary Sjogren's syndrome: a case report.

ABSTRACT:

Background

Primary Sjögren's syndrome (pSS) is a chronic autoimmune inflammatory disorder primarily affecting the exocrine glands. A subset of patients exhibits extraglandular manifestations, including cardiovascular involvement. Among them, myocarditis is a rare complication, and its pathogenesis remains poorly understood.

Case presentation

An 85-year-old man with a persistent dry mouth was admitted to our hospital with high-grade fever, nausea, fatigue, and urinary disturbance. On day 2, the patient developed multiple cerebral infarctions and bilateral acute otitis media. Fever and inflammatory response without leukocytosis and cardiac imaging findings indicative of active myocarditis, and normal cardiac function suggested acute viral myocarditis, for which supportive trea

SUBMITTER: Hashimoto K 

PROVIDER: S-EPMC12541781 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature