The evolving role of wedge resection in early-stage non-small cell lung cancer: a literature review.

ABSTRACT:

Background and objective

The surgical management of early-stage non-small cell lung cancer (NSCLC) is evolving due to advances in imaging, staging, and individualized patient selection. Although lobectomy has historically been the gold standard for stage I operable NSCLC, the detection of smaller peripheral tumors and minimally invasive techniques have revived interest in sublobar resections, especially wedge resection. This review aims to critically examine the current and potential role of wedge resection in this context.

Methods

A narrative review was conducted using literature retrieved from PubMed, Scopus, and Google Scholar, covering the period from January 2000 to March 2024. Keywords included "non-small cell lung cancer", "wedge resection", "sublobar resection", and

SUBMITTER: Ceccarelli I 

PROVIDER: S-EPMC12541856 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature