Mapping Human Proprioceptive Projections of Upper Limb Muscles Through Spinal Cord fMRI.

ABSTRACT: The functional organization of the human spinal cord has primarily been derived from clinical observations and invasive electrophysiological studies. Recent methodological advances opened the possibility of studying the neuronal activity of the spinal cord in humans using noninvasive functional magnetic resonance imaging (fMRI). Here, we took advantage of fMRI to map the patterns of activity elicited by muscle-specific proprioceptive information along the whole cervical cord. We quantified the fMRI signals of the cervical spinal cord in 24 healthy participants who received mechanical muscle tendon vibration to stimulate proprioceptive afferents. The wrist flexor, biceps, and anterior deltoid muscles were independently stimulated while the upper limbs were stationary to avoid movement artif

SUBMITTER: Schlienger R 

PROVIDER: S-EPMC12541885 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature