Association between long-term exposure to air pollutant mixture and the risk of Alzheimer's disease among older people: a prospective cohort study in China.

ABSTRACT:

Background

Alzheimer's disease (AD) has garnered significant attention in recent years. However, evidence of the association between air pollutant mixture and AD from prospective studies has not been systematically explored. We aimed to examine the associations of combined exposure to nitrogen dioxide (NO₂), sulfur dioxide (SO₂), ozone (O₃), and particulate matter (PM) with diameters of ≤ 2.5 μm (PM_2.5) or ≤ 10 μm (PM₁₀) with AD, and to further investigate the potential modifiable effects of lifestyle factors and air pollution.

Methods

Our study was based on the Zhejiang Province Major Public Health Surveillance (ZJMPHS) Program. The concentrations of five air pollutants were estimated via the empirical Bayesian kriging

SUBMITTER: Fu H 

PROVIDER: S-EPMC12541937 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature