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Bridging the gap between evidence and clinical practice for migraine headaches: a systematic review (2019-2024).


ABSTRACT:

Background

Migraine headache (MH) is a prevalent and complex neurological disorder affecting over one billion individuals worldwide, making it one of the leading causes of years lived with disability. Randomized controlled trials (RCTs) support evidence-based neurology, but whether recent trials provide practice-ready information remains unclear. This study aims to identify common shortcomings in design and reporting; highlight trial features that enhance value to practicing clinicians; and offer recommendations that improve the alignment between MH research and patient-centered care.

Methods

We systematically reviewed RCTs focused on acute or preventive MH interventions indexed in Embase and MEDLINE from January 1, 2019, to December 31, 2024, against a 13-item usefulness cr

SUBMITTER: Chen E 

PROVIDER: S-EPMC12542087 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature