Clinical manifestations and quality of life of postmenopausal women with severe osteoporosis: a cross-sectional study on the Vietnamese population.

ABSTRACT:

Background

Osteoporosis, a systemic skeletal disorder characterized by reduced bone mineral density (BMD) and micro-architectural deterioration, significantly increases fracture risk. Postmenopausal women are particularly susceptible due to estrogen deficiency, which accelerates bone resorption. This study evaluates the clinical manifestations and quality of life (QoL) of Vietnamese women with severe postmenopausal osteoporosis using the Quality of Life Questionnaire of the European Foundation for Osteoporosis (Qualeffo-41).

Methods

A cross-sectional study was conducted from February to May 2023 at Nghe An Friendship General Hospital, Vietnam. Seventy-one postmenopausal women aged 48-94 years with severe osteoporosis (BMD T-score ≤ -2.5 SD and history of fracture) were inclu

SUBMITTER: Nguyen CT 

PROVIDER: S-EPMC12542133 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature